"Orthostatic Intolerance" is a rare disease. Anyone diagnosed with it could mean the person has to retire for a few years, or forever. If the person with the tolerance stands up, it's heart can't pump enough blood through the blood vessels so they can only stand for a limited amount of time. Side effects are fatigue and loss of balance. It affects more females than males. Greg Page, former yellow Wiggle, is among those who have this condition.